GHRP 2 (Growth Hormone Releasing Peptide – 2)
GHRPs are a small family of peptides acting at the pituitary and the hypothalamus to release Growth hormone (GH) through the activation of a specific, G protein-coupled receptor.
They were discovered 20 years ago as synthetic metenkephalin- derived oligopeptides (Synthetic tissue derived amino acids). Although it has no structural homology with Growth Hormone Releasing Hormone (GHRH), in clinical studies GHRP-2 demonstrated action on the pituitary to release Human Growth Hormone (HGH). Similar results were effective when GHRP-2 was administered sublingual. Clinical studies showed the most potent GHRP being the hexapeptide GHRP-2.
Growth Hormone Releasing Peptide 2(GHRP2) substantially stimulates the pituitary gland’s increased natural production of the body’s own endogenous human growth hormone (HGH). This therapy consists of daily periodic sub-lingual dosing. Growth Hormone releasing peptide 2, GHRP2 has shown on it’s own to robustly increase IGF-1 levels, and even greater results occurred when used with Growth Hormone Releasing Hormone (GHRH) to which also stimulates the pituitary gland to produce increased natural secretion of human growth hormone. This also boosts the hypothalamus function as well.
The results of the clinical studies published in the Journal of Endocrinology and Metabolism in 1997 for GHRP2 – showed that a medically supervised, prescribed and administered therapy increased growth hormone levels in adults and children, who have growth hormone GHRP2_07deficiency.
The increase in the body’s growth hormone via elevated IGF-1 levels produced by the pituitary gland in response to GHRP2 therapy — has an anabolic effect on the tissues of the body and other benefits identified below.
GHRP2 growth hormone releasing peptide2 therapy is considered one of a few medical means of reversing the effects of aging in adults deficient in growth hormone. This is because of the benefits resulting from the increased stimulation and secretion of human growth hormone by the pituitary gland hypothalamus,axis HPA.